Meta-Analysishigh evidence
Injection of Leukocyte-Poor Platelet-Rich Plasma During Rotator Cuff Repair Can Increase Healing Rate but Does Not Affect Clinical Outcomes: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·September 12, 2026·PMID 42732080
Why it mattersRotator cuff repair failure remains a significant clinical problem, and biologic augmentation with LP-PRP may improve tendon healing. This analysis clarifies that while LP-PRP reduces structural failure, the functional gains are too small to be clinically meaningful, guiding realistic patient counseling and expectations.
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