Randomized Trialhigh evidence
Slowing Cognitive Decline in Major Depressive Disorder and Mild Cognitive Impairment: A Randomized Clinical Trial.
JAMA psychiatry·January 1, 2025·PMID 39476073
Why it mattersThis is the first large RCT to show that a combined CR and tDCS intervention can slow long-term cognitive decline in a high-risk population, offering a potential non-pharmacological strategy for prevention.

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