Meta-Analysisvery high evidence
Endovascular thrombectomy for patients with large-core ischaemic stroke presenting up to 24 h after onset (ATLAS): a systematic review and individual patient data meta-analysis with central imaging adjudication.
Lancet (London, England)·May 23, 2026·PMID 42107392
Why it mattersThis meta-analysis strengthens the evidence for extending endovascular thrombectomy to patients with large-core strokes, a group often excluded from earlier trials. It provides pooled, centrally adjudicated data supporting treatment benefit up to 24 hours, which can guide specialist decision-making in emergency settings.
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