Randomized Trialhigh evidence

A Randomized Controlled Trial of Mild Hyperbaric Oxygen Therapy on Cognitive Performance and Sleep Quality in Healthy Young Adults at High Altitude: Exploratory Functional Near-Infrared Spectroscopy study.

Travel medicine and infectious disease·July 21, 2026·PMID 42480892

Why it matters

High-altitude exposure impairs sleep and cognition, limiting performance in military, athletic, and occupational settings. This trial provides mechanistic and clinical evidence that a brief, non-pharmacologic mHBOT protocol can mitigate these deficits, offering a practical countermeasure for individuals operating in hypoxic environments.

Infographic summary of A Randomized Controlled Trial of Mild Hyperbaric Oxygen Therapy on Cognitive Performance and Sleep Quality in Healthy Young Adults at High Altitude: Exploratory Functional Near-Infrared Spectroscopy study.
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