Randomized Trialmoderate evidence
Effect of transdermal testosterone on postmenopausal sexual desire: placebo-controlled randomized clinical trial.
European journal of obstetrics, gynecology, and reproductive biology·August 1, 2026·PMID 42302467
Why it mattersTransdermal testosterone is used off-label for hypoactive sexual desire in postmenopausal women, but evidence on compounded formulations is limited. This study provides efficacy and safety signals relevant to clinicians managing sexual health in menopause.

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