Randomized Trialhigh evidence

Brain stimulation prevents neural downregulation and optimizes learning.

NeuroImage·April 1, 2026·PMID 41724411

Why it matters

Cognitive training often fails to produce behavioral gains due to rapid neural adaptation in higher-order attentional areas. This study provides mechanistic evidence that tRNS can sustain cortical excitability during learning, offering a potential strategy to enhance neuroplasticity and optimize cognitive interventions in both healthy and clinical populations.

Infographic summary of Brain stimulation prevents neural downregulation and optimizes learning.
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