Randomized Trialhigh evidence

Desmodium styracifolium Total Flavone Capsules for Urolithiasis: A Phase 3 Randomized Clinical Trial.

JAMA network open·September 1, 2026·PMID 42714908

Why it matters

No oral medication is currently approved for urolithiasis, and medical expulsive therapy options are limited. This trial provides high-level evidence that a traditional Chinese herbal extract may improve stone passage for appropriately selected patients, potentially offering a new non-invasive treatment option.

Infographic summary of Desmodium styracifolium Total Flavone Capsules for Urolithiasis: A Phase 3 Randomized Clinical Trial.
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