Randomized Trialhigh evidence
Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 10-year efficacy and late normal tissue effects from a multicentre, open-label, non-inferiority, phase 3, randomised controlled trial and 5-year efficacy results from a randomised axillary substudy.
The Lancet. Oncology·June 1, 2026·PMID 42134381
Why it mattersThis provides long-term evidence that a 1-week schedule is safe and effective, supporting its adoption as a standard of care. It reduces treatment burden for patients and healthcare systems without compromising outcomes.

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