Meta-Analysismoderate evidence
Platelet-rich plasma provides greater pain relief and functional improvement than hyaluronic acid for knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials.
Journal of ISAKOS : joint disorders & orthopaedic sports medicine·September 15, 2026·PMID 42744121
Why it mattersKnee osteoarthritis is a leading cause of pain-related disability, and intra-articular injections are common when conservative care fails. This meta-analysis provides comparative effectiveness data to guide choice between PRP and HA, particularly regarding patient selection and injection protocols.
The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled