Randomized Trialhigh evidence

The Cognitive benefits of nitrate in patients with alcohol use disorder: unraveling the oral microbiome ectopic colonization pathway.

Molecular psychiatry·April 9, 2026·PMID 41957179

Why it matters

AUD-related cognitive decline lacks effective treatments. This study identifies a safe, dietary intervention that may improve cognition and highlights a novel oral-gut-brain axis mechanism, opening avenues for microbiota-targeted therapies in addiction medicine.

Infographic summary of The Cognitive benefits of nitrate in patients with alcohol use disorder: unraveling the oral microbiome ectopic colonization pathway.
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