Randomized Trialhigh evidence
Sleep-Aligned Extended Overnight Fasting Improves Nighttime and Daytime Cardiometabolic Function.
Arteriosclerosis, thrombosis, and vascular biology·April 1, 2026·PMID 41674465
Why it mattersFor clinicians counseling patients on lifestyle-based cardiometabolic risk reduction, this study suggests that meal timing relative to sleep may matter, not just fasting duration. A practical recommendation to stop eating at least 3 hours before bedtime may modestly improve nocturnal blood pressure regulation and next-morning glucose handling.
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