Randomized Trialhigh evidence

Resistance training tempo selectively modulates corticospinal and reticulospinal excitability in humans.

The Journal of physiology·April 1, 2026·PMID 41845576

Why it matters

Training tempo is often overlooked in exercise prescription, yet this study demonstrates it is a physiologically meaningful variable that can direct neuroplasticity toward distinct motor pathways. For specialists in performance and longevity, understanding how to target the reticulospinal tract—critical for rapid force production and postural control—versus corticospinal pathways may optimize training for specific functional outcomes, such as explosive power or motor learning.

Infographic summary of Resistance training tempo selectively modulates corticospinal and reticulospinal excitability in humans.
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