Randomized Trialmoderate evidence
TASTY AND HEALTHY DIET REDUCES FECAL CALPROTECTIN IN HIGH-RISK FIRST-DEGREE RELATIVES OF PATIENTS WITH CROHN'S DISEASE: PIONIR RANDOMIZED CROSSOVER TRIAL.
Gastroenterology·October 26, 2026·PMID 42933673
Why it mattersPreventing Crohn's disease in high-risk individuals is a major unmet need. This trial shows that a specific diet can reduce subclinical intestinal inflammation, a potential precursor to disease, offering a feasible preventive strategy.
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