Randomized Trialhigh evidence
Pulsed Field Ablation Versus Sham to Treat Atrial Fibrillation: The PFA-SHAM Randomized Clinical Trial.
Circulation·June 23, 2026·PMID 42186803
Why it mattersThis is the first sham-controlled trial for PFA, providing robust evidence that the benefits of AF ablation extend beyond placebo effects, particularly for subjective outcomes like quality of life and anxiety, which are critical to patient-centered care.
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