Meta-Analysishigh evidence
Exploring Between-Study Heterogeneity in Extended-Window IV Thrombolysis for Acute Ischemic Stroke: A Meta-Analysis of 18 Randomized Controlled Trials.
Neurology·August 11, 2026·PMID 42475651
Why it mattersExtended-window IVT offers a reperfusion option for the many acute ischemic stroke patients who present beyond 4.5 hours or lack timely access to thrombectomy, expanding the treatment-eligible population and potentially improving outcomes in resource-limited settings.

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