Basic Sciencelow evidence
PCET-Inspired Nanoparticles Enable Paired Proton-Electron Delivery to Restore Mitochondrial Electron Transport and Regenerate Bone During Aging.
Advanced materials (Deerfield Beach, Fla.)·July 20, 2026·PMID 42473758
Why it mattersAging impairs mitochondrial bioenergetics, limiting tissue repair. This nanotherapeutic approach directly targets mitochondrial electron transport chain dysfunction in senescent cells, offering a potential strategy to rejuvenate aged regenerative niches without drugs.
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