Randomized Trialhigh evidence
Long-term microbiome and clinical effects of a microbiome-guided personalized diet versus low-FODMAP diet in irritable bowel syndrome: A 12-month follow-up randomized controlled trial.
Gut microbes·December 31, 2026·PMID 42623122
Why it mattersLong-term dietary management of IBS is challenging, and low-FODMAP diets often lose effectiveness over time. This study suggests that microbiome-guided personalization may offer more durable symptom relief and better quality of life, addressing a key limitation of current dietary approaches.
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