Randomized Trialhigh evidence

Ketone Monoester, With and Without Caffeine, Prevents Mental Fatigue and Preserves Cognitive Performance.

Journal of strength and conditioning research·July 10, 2026·PMID 42429835

Why it matters

Cognitive resilience under fatigue is critical for athletes and tactical professionals. This study provides evidence that acute nutritional ketosis, especially when combined with caffeine, can preserve executive function during demanding tasks, offering a potential ergogenic strategy for sustained mental performance.

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