Randomized Trialhigh evidence
Ketone monoester ingestion and cognitive and physical performance during exercise-heat stress.
Journal of the International Society of Sports Nutrition·December 31, 2026·PMID 42460838
Why it mattersSustaining cognitive and physical performance during exercise-heat stress is critical for tactical athletes and others operating in extreme environments. This study provides initial evidence that a ketone monoester with caffeine may selectively enhance working memory and endurance without increasing cardiovascular or thermal strain, offering a potential nutritional strategy for maintaining performance under combined physical and thermal load.
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