Meta-Analysishigh evidence
Intravenous Thrombolysis Beyond the Conventional Time Window for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.
JAMA network open·August 3, 2026·PMID 42560675
Why it mattersMany stroke patients present beyond 4.5 hours or with unknown onset, and this analysis confirms that imaging-based selection can identify those who still benefit from thrombolysis, informing acute treatment decisions in emergency and neurology settings.
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