Randomized Trialmoderate evidence

Lifespan exposure to hormone therapies and structural brain morphometry in older women.

NeuroImage·July 1, 2026·PMID 42082089

Why it matters

Understanding how reproductive hormone exposures across the lifespan influence brain structure can inform risk assessment and counseling for cognitive aging in women, a population disproportionately affected by Alzheimer's disease.

Infographic summary of Lifespan exposure to hormone therapies and structural brain morphometry in older women.
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