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Role of the Upper Motor Neuron in the Generation of Fasciculations in Early Disease Stages of Amyotrophic Lateral Sclerosis.
Neurology·July 28, 2026·PMID 42407013
Why it mattersThis paper provides mechanistic insight into fasciculation generation in early ALS, highlighting the role of cortical hyperexcitability. It may help neurologists differentiate ALS-related fasciculations from benign or other neurogenic fasciculations, potentially aiding earlier diagnosis.
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