Basic Sciencemoderate evidence
Multiomic profiling of responses to clinical and novel bisphosphonates reveals extraskeletal effects on ageing related signatures.
Signal transduction and targeted therapy·July 15, 2026·PMID 42448670
Why it mattersBisphosphonates are widely used for bone loss, but emerging evidence suggests they may have geroprotective effects across multiple organs. This study provides mechanistic insight into how these drugs could counteract fundamental aging processes, potentially expanding their therapeutic relevance for longevity and age-related functional decline.
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