Randomized Trialhigh evidence

Supplementation with lutein and zeaxanthin increases macular pigment optical density and cognitive performance in healthy teenagers in a randomized, double-blind, placebo-controlled trial.

Nutrition research (New York, N.Y.)·August 1, 2026·PMID 42413424

Why it matters

This is the first RCT to show that lutein and zeaxanthin supplementation can enhance both macular pigment and specific cognitive functions in teenagers, a population with high screen exposure and often poor dietary intake of these carotenoids. It suggests a potential nutritional strategy for supporting eye and brain health during adolescence.

Infographic summary of Supplementation with lutein and zeaxanthin increases macular pigment optical density and cognitive performance in healthy teenagers in a randomized, double-blind, placebo-controlled trial.
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