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Spinal cord stimulation for the treatment of painful diabetic neuropathy and risk of major adverse cardiovascular events, mortality, amputation, infection and suicide: a retrospective cohort study.

EClinicalMedicine·November 1, 2025·PMID 41079020

Why it matters

Painful diabetic neuropathy is common and difficult to treat. This study provides real-world evidence that SCS may reduce not only pain but also serious downstream complications like cardiovascular events and amputations, which are major concerns for these patients.

Infographic summary of Spinal cord stimulation for the treatment of painful diabetic neuropathy and risk of major adverse cardiovascular events, mortality, amputation, infection and suicide: a retrospective cohort study.
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