Cohort Studymoderate evidence
Spinal cord stimulation for the treatment of painful diabetic neuropathy and risk of major adverse cardiovascular events, mortality, amputation, infection and suicide: a retrospective cohort study.
EClinicalMedicine·November 1, 2025·PMID 41079020
Why it mattersPainful diabetic neuropathy is common and difficult to treat. This study provides real-world evidence that SCS may reduce not only pain but also serious downstream complications like cardiovascular events and amputations, which are major concerns for these patients.

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