Cohort Studyhigh evidence
Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment.
JAMA·July 14, 2026·PMID 42449500
Why it mattersPlasma p-tau217 provides time-specific absolute risk estimates for progression to cognitive impairment in cognitively unimpaired older adults, supporting its use in prognostic models and trial enrichment.

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