Randomized Trialhigh evidence
12‑weeks fisetin supplementation and interval resistance with aerobic training: changes in Maresin‑1 and inflammatory markers in men with obesity: a randomized controlled trial.
Journal of the International Society of Sports Nutrition·December 31, 2026·PMID 42218768
Why it mattersMaresin-1 is a pro-resolving mediator with limited human interventional data. This study provides early evidence that exercise and fisetin can upregulate resolution pathways and improve metabolic health in obesity, relevant for specialists exploring non-pharmacological strategies to mitigate chronic inflammation and insulin resistance.
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