Cohort Studymoderate evidence
Delayed gastric emptying in adolescent patients on GLP-1 receptor agonists with standard preoperative fasting guidelines: a prospective cohort study.
British journal of anaesthesia·September 8, 2026·PMID 42711215
Why it mattersGLP-1 receptor agonists are increasingly prescribed to adolescents for diabetes and obesity, yet standard preoperative fasting may not ensure an empty stomach. This study provides direct evidence that these patients frequently retain solid gastric contents, raising concerns for perioperative aspiration risk and the need for modified fasting or airway management strategies.
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