Meta-Analysismoderate evidence
Drug treatments for fibromyalgia: systematic review and network meta-analysis of randomised trials.
BMJ medicine·January 1, 2026·PMID 42851751
Why it mattersFibromyalgia management often involves multiple drug classes with uncertain comparative benefits. This network meta-analysis provides a comprehensive overview of available options, highlighting that while some drugs may offer modest benefits in specific outcomes, none demonstrated clinically important improvements in pain or overall function. Clinicians can use these findings to set realistic expectations and tailor treatment choices based on individual patient priorities.
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