Randomized Trialhigh evidence
Immune Modulation by Personalized vs Standard Prehabilitation Before Major Surgery: A Randomized Clinical Trial.
JAMA surgery·January 1, 2026·PMID 41222945
Why it mattersFor perioperative and rehabilitation specialists, this study suggests that how prehabilitation is delivered matters: individualized coaching may improve functional readiness and reduce complications, with biologic signals consistent with lower perioperative inflammatory activation.

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