Randomized Trialhigh evidence

Immune Modulation by Personalized vs Standard Prehabilitation Before Major Surgery: A Randomized Clinical Trial.

JAMA surgery·January 1, 2026·PMID 41222945

Why it matters

For perioperative and rehabilitation specialists, this study suggests that how prehabilitation is delivered matters: individualized coaching may improve functional readiness and reduce complications, with biologic signals consistent with lower perioperative inflammatory activation.

Infographic summary of Immune Modulation by Personalized vs Standard Prehabilitation Before Major Surgery: A Randomized Clinical Trial.
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