Randomized Trialhigh evidence
Testosterone Treatment and Sexual Function in Men: Secondary Analysis of the T4DM (Testosterone for Diabetes) Trial.
The Journal of clinical endocrinology and metabolism·June 17, 2025·PMID 39928571
Why it mattersSexual dysfunction is common in men with metabolic risk, and this trial clarifies that testosterone therapy can improve sexual desire and, to a lesser degree, erectile function, especially in older men or those with depressive symptoms. It also reinforces the independent benefits of lifestyle changes.

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