Meta-Analysismoderate evidence
Hemoperfusion during extracorporeal membrane oxygenation: an updated systematic review and meta-analysis of 8,151 patients.
Critical care (London, England)·July 19, 2026·PMID 42472846
Why it mattersHemoperfusion is sometimes used with ECMO to remove inflammatory mediators, but its benefit is unproven. This meta-analysis suggests no survival advantage and a potential harm signal from RCTs, which should caution clinicians against routine use.
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