Randomized Trialhigh evidence

Effect of Intravenous, Inhalational, or Combined Anesthesia Maintenance on Postoperative Respiratory Adverse Events in Children Undergoing Adenotonsillectomy (AmPRAEC): A Multicenter Randomized Clinical Trial.

Anesthesiology·December 1, 2025·PMID 40768554

Why it matters

Postoperative respiratory adverse events are common and potentially serious in children after adenotonsillectomy. This trial provides high-quality evidence that anesthesia maintenance choice directly impacts risk, offering a modifiable factor to improve safety.

Infographic summary of Effect of Intravenous, Inhalational, or Combined Anesthesia Maintenance on Postoperative Respiratory Adverse Events in Children Undergoing Adenotonsillectomy (AmPRAEC): A Multicenter Randomized Clinical Trial.
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