Meta-Analysishigh evidence
Effects of Omega-3 Fatty Acid Treatment on Risk for Atrial Fibrillation: An Updated Meta-Analysis of 35 Trials including 114 592 Individuals.
Circulation. Arrhythmia and electrophysiology·July 28, 2026·PMID 42517224
Why it mattersClinicians prescribing omega-3 fatty acids for cardiovascular risk reduction must weigh the potential for increased atrial fibrillation risk, particularly when using high doses in patients with elevated cardiovascular risk. This analysis clarifies that the AF signal is dose- and risk-dependent, informing patient selection and monitoring strategies.
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