Randomized Trialhigh evidence
Sleep Management Combined With Rehabilitation Exercise to Alleviate Chronic Pain Following Total Knee Arthroplasty: A Randomized Controlled Trial.
The Journal of arthroplasty·July 1, 2026·PMID 41173158
Why it mattersChronic pain after TKA is common and difficult to manage with medications alone. This study provides evidence that addressing sleep and psychological factors alongside physical rehabilitation can improve multiple outcomes, offering a practical, nonpharmacologic strategy for pain specialists and orthopedic surgeons.

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