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Cardiometabolic trade-offs of carbohydrate- and fat-focused diets: a network meta-analysis of randomised clinical trials.

European journal of nutrition·July 8, 2026·PMID 42418007

Why it matters

Clinicians managing cardiovascular risk need to understand the trade-offs of popular dietary patterns: carbohydrate restriction may improve triglycerides, HDL, and adiposity but can worsen LDL cholesterol, especially with ketogenic approaches. This informs personalized dietary counseling based on individual lipid profiles and risk factors.

Infographic summary of Cardiometabolic trade-offs of carbohydrate- and fat-focused diets: a network meta-analysis of randomised clinical trials.
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