Meta-Analysishigh evidence
Cardiometabolic trade-offs of carbohydrate- and fat-focused diets: a network meta-analysis of randomised clinical trials.
European journal of nutrition·July 8, 2026·PMID 42418007
Why it mattersClinicians managing cardiovascular risk need to understand the trade-offs of popular dietary patterns: carbohydrate restriction may improve triglycerides, HDL, and adiposity but can worsen LDL cholesterol, especially with ketogenic approaches. This informs personalized dietary counseling based on individual lipid profiles and risk factors.

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