Systematic Reviewvery low evidence
Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta-analysis.
Addiction (Abingdon, England)·July 22, 2026·PMID 42483790
Why it mattersCocaine use disorder lacks any approved pharmacotherapy, and clinicians frequently encounter patients seeking treatment. This comprehensive synthesis confirms that current evidence does not support routine use of any medication, helping clinicians avoid ineffective prescribing and set realistic expectations with patients.
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