Randomized Trialhigh evidence

Distinct effects of ketogenic and non-ketogenic weight-loss diets on hepatic steatosis and mitochondrial metabolism in MASLD.

Journal of hepatology·July 1, 2026·PMID 41655910

Why it matters

This study provides mechanistic insight into how dietary composition, beyond calorie restriction, affects liver fat and mitochondrial function in MASLD, highlighting a potential trade-off between rapid fat reduction and metabolic changes that may increase liver injury risk.

Infographic summary of Distinct effects of ketogenic and non-ketogenic weight-loss diets on hepatic steatosis and mitochondrial metabolism in MASLD.
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