Mortality effect of albumin fluid resuscitation in adults with septic shock: a systematic review and dual frequentist-bayesian meta-analysis of randomised trials.

Critical care (London, England)·July 6, 2026·PMID 42410446

Why it matters

Fluid resuscitation is a cornerstone of septic shock management, yet the optimal choice between albumin and crystalloids remains debated. This meta-analysis provides updated evidence suggesting a modest mortality reduction with albumin, which may influence resuscitation protocols in emergency departments and ICUs.