Basic Sciencelow evidence
Ultrasound-Mediated OFF-to-ON Switching of Bone Regeneration via a Bioorthogonal Cell-Capture Hydrogel, Enabling Spatiotemporal Control and Monitoring.
Advanced materials (Deerfield Beach, Fla.)·July 11, 2026·PMID 42433127
Why it mattersCurrent stem cell therapies for critical-sized bone defects suffer from poor engraftment and lack of control over cell fate. This platform offers a solution by covalently capturing cells at the defect site and using ultrasound to both monitor and remotely trigger osteogenic differentiation, potentially improving the precision and efficacy of regenerative treatments.
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