Randomized Trialmoderate evidence
Adaptive deep brain stimulation for dynamic gait control in Parkinson's disease: a randomized feasibility trial.
Nature medicine·June 15, 2026·PMID 42297980
Why it mattersGait dysfunction in Parkinson's disease often responds poorly to conventional continuous DBS. This study demonstrates that temporally precise, behavior-contingent neuromodulation is feasible and may address a critical unmet need—reducing falls—by synchronizing stimulation to individual gait cycles.
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