Randomized Trialmoderate evidence
The Effect of a Very Low-Carbohydrate Diet on Intermuscular Adipose Tissue and Muscle Function in Older Adults With Obesity.
Obesity (Silver Spring, Md.)·November 1, 2026·PMID 42838121
Why it mattersIMAT accumulation is linked to poor muscle quality and mobility decline in older adults with obesity. This trial shows that a short-term VLCD can substantially reduce IMAT and that this reduction tracks with functional gains, suggesting a dietary strategy to target a specific fat depot implicated in sarcopenia and disability.
The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled