Randomized Trialhigh evidence

Comparative Effectiveness and Safety of Percutaneous Balloon Compression Versus Conventional Radiofrequency Thermocoagulation for Classic Trigeminal Neuralgia: A Randomized Clinical Trial.

Pain physician·May 1, 2026·PMID 42263309

Why it matters

This is the first randomized evidence directly comparing two common percutaneous procedures for trigeminal neuralgia, providing data to guide procedural selection. PBC demonstrated superior pain relief at 6 months with a comparable safety profile, which may influence treatment algorithms for patients failing medical therapy.

Infographic summary of Comparative Effectiveness and Safety of Percutaneous Balloon Compression Versus Conventional Radiofrequency Thermocoagulation for Classic Trigeminal Neuralgia: A Randomized Clinical Trial.
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