Randomized Trialhigh evidence
Prevention of type 2 diabetes through prediabetes remission without weight loss.
Nature medicine·October 1, 2025·PMID 41023486
Why it mattersCurrent guidelines emphasize weight loss for diabetes prevention, but this study shows that achieving normoglycemia—even without weight loss—is a stronger protective factor. It highlights the importance of monitoring glycemic targets, not just weight, in prediabetes management.
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