Randomized Trialhigh evidence
Effect of Testosterone on Progression From Prediabetes to Diabetes in Men With Hypogonadism: A Substudy of the TRAVERSE Randomized Clinical Trial.
JAMA internal medicine·April 1, 2024·PMID 38315466
Why it mattersMany men with hypogonadism also have prediabetes or diabetes, and TRT is often considered for metabolic benefits. This large RCT provides high-quality evidence that TRT alone does not alter diabetes risk or glycemic control, helping clinicians avoid ineffective off-label use.
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