Meta-Analysishigh evidence
Optimal Route of Tranexamic Acid Administration in Total Knee Arthroplasty: A Bayesian Network Meta-Analysis with Decision-Analytic Cost Evaluation.
The Journal of arthroplasty·June 29, 2026·PMID 42373027
Why it mattersOrthopedic surgeons need evidence-based guidance on TXA route selection that balances efficacy, safety, cost, and ease of use. This analysis clarifies that oral TXA offers a pragmatic, cost-effective default for routine primary TKA without sacrificing safety.
The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled