Randomized Trialvery high evidence
Twice-Yearly Lenacapavir or Daily F/TAF for HIV Prevention in Cisgender Women.
The New England journal of medicine·October 3, 2024·PMID 39046157
Why it mattersThis trial demonstrates that a twice-yearly injectable PrEP option can achieve zero HIV infections in a high-incidence population of young women, addressing major adherence challenges with daily oral PrEP. It offers a highly effective, long-acting alternative that could transform HIV prevention strategies in this vulnerable group.

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