Randomized Trialhigh evidence

Intraoperative dexmedetomidine reduces postoperative sleep disturbance in older adults undergoing major abdominal surgery: a single-center, randomized, double-blind, placebo-controlled trial.

Communications medicine·July 3, 2026·PMID 42399418

Why it matters

Postoperative sleep disturbance is common after major surgery and impairs recovery. This trial provides strong evidence that a simple intraoperative intervention can markedly improve sleep, which may enhance recovery and patient experience.

Infographic summary of Intraoperative dexmedetomidine reduces postoperative sleep disturbance in older adults undergoing major abdominal surgery: a single-center, randomized, double-blind, placebo-controlled trial.
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