Cohort Studyhigh evidence
The Role of Coronary Artery Calcium in Statin Eligibility Based on the American Heart Association's PREVENT Calculator: Insights From MESA.
Journal of the American College of Cardiology·July 7, 2026·PMID 42455102
Why it mattersThe 2026 dyslipidemia guidelines incorporate PREVENT equations, and clinicians need evidence on how CAC scoring can refine risk assessment in this new framework. This study clarifies that CAC is most useful for reclassifying borderline risk, but CAC=0 does not negate the need for statins in higher-risk patients already meeting treatment thresholds.
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