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A Multicenter Randomized Pragmatic Trial Comparing Intra-Articular Injection, Genicular Nerve Block, and Radiofrequency Ablation for Knee Osteoarthritis Pain: SKOAP Phase 2 Protocol.
Pain medicine (Malden, Mass.)·July 3, 2026·PMID 42397214
Why it mattersThis trial will provide the most methodologically robust head-to-head comparative evidence on procedural escalation for knee OA pain, directly informing guidelines and clinical decision-making on when to advance from injections to nerve blocks or ablation.
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